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TargetMonoglyceride lipase (MGL)
LigandBDBM50274153
Substrate/Competitorn/a
Meas. Tech.ChEMBL_537181
Ki 39000±n/a nM
Citation Magrioti VNaxakis GHadjipavlou-Litina DMakriyannis AKokotos G A novel monoacylglycerol lipase inhibitor with analgesic and anti-inflammatory activity. Bioorg Med Chem Lett 18:5424-7 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Monoglyceride lipase (MGL)
Name:Monoglyceride lipase (MGL)
Synonyms:MAGL | Monoacylglycerol lipase | Monoglyceride lipase
Type:Enzyme
Mol. Mass.:33505.38
Organism:Rattus norvegicus (Rat)
Description:Q8R431
Residue:303
Sequence:
MPEASSPRRTPQNVPYQDLPHLVNADGQYLFCRYWKPSGTPKALIFVSHGAGEHCGRYDE
LAQMLKRLDMLVFAHDHVGHGQSEGERMVVSDFQVFVRDLLQHVNTVQKDYPEVPVFLLG
HSMGGAISILAAAERPTHFSGMILISPLILANPESASTLKVLAAKLLNFVLPNISLGRID
SSVLSRNKSEVDLYNSDPLICHAGVKVCFGIQLLNAVSRVERAMPRLTLPFLLLQGSADR
LCDSKGAYLLMESSPSQDKTLKMYEGAYHVLHKELPEVTNSVLHEINTWVSHRIAVAGAR
CLP
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  Blast E-value cutoff:
BDBM50274153
n/a
NameBDBM50274153
Synonyms:(2R,9Z)-octadec-9-ene-1,2-diamine dihydrochloride | CHEMBL485371
TypeSmall organic molecule
Emp. Form.C18H38N2
Mol. Mass.282.5077
SMILESCCCCCCCC\C=C/CCCCCC[C@@H](N)CN |r|
Structure
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