Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetMonoglyceride lipase
LigandBDBM50274152
Substrate/Competitorn/a
Meas. Tech.ChEMBL_537181 (CHEMBL992557)
Ki 21800±n/a nM
Citation Magrioti, VNaxakis, GHadjipavlou-Litina, DMakriyannis, AKokotos, G A novel monoacylglycerol lipase inhibitor with analgesic and anti-inflammatory activity. Bioorg Med Chem Lett18:5424-7 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Monoglyceride lipase
Name:Monoglyceride lipase
Synonyms:MAGL | MGLL_RAT | Mgl2 | Mgll | Monoacylglycerol lipase | Monoglyceride lipase | Monoglyceride lipase (MGL)
Type:Enzyme
Mol. Mass.:33505.38
Organism:Rattus norvegicus (Rat)
Description:Q8R431
Residue:303
Sequence:
MPEASSPRRTPQNVPYQDLPHLVNADGQYLFCRYWKPSGTPKALIFVSHGAGEHCGRYDE
LAQMLKRLDMLVFAHDHVGHGQSEGERMVVSDFQVFVRDLLQHVNTVQKDYPEVPVFLLG
HSMGGAISILAAAERPTHFSGMILISPLILANPESASTLKVLAAKLLNFVLPNISLGRID
SSVLSRNKSEVDLYNSDPLICHAGVKVCFGIQLLNAVSRVERAMPRLTLPFLLLQGSADR
LCDSKGAYLLMESSPSQDKTLKMYEGAYHVLHKELPEVTNSVLHEINTWVSHRIAVAGAR
CLP
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50274152
n/a
NameBDBM50274152
Synonyms:(2S,9Z)-octadec-9-ene-1,2-diamine dihydrochloride | CHEMBL500707
TypeSmall organic molecule
Emp. Form.C18H38N2
Mol. Mass.282.5077
SMILESCCCCCCCC\C=C/CCCCCC[C@H](N)CN |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: