Reaction Details |
| Report a problem with these data |
Target | Monoglyceride lipase |
---|
Ligand | BDBM50274152 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_537181 (CHEMBL992557) |
---|
Ki | 21800±n/a nM |
---|
Citation | Magrioti, V; Naxakis, G; Hadjipavlou-Litina, D; Makriyannis, A; Kokotos, G A novel monoacylglycerol lipase inhibitor with analgesic and anti-inflammatory activity. Bioorg Med Chem Lett18:5424-7 (2008) [PubMed] Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Monoglyceride lipase |
---|
Name: | Monoglyceride lipase |
Synonyms: | MAGL | MGLL_RAT | Mgl2 | Mgll | Monoacylglycerol lipase | Monoglyceride lipase | Monoglyceride lipase (MGL) |
Type: | Enzyme |
Mol. Mass.: | 33505.38 |
Organism: | Rattus norvegicus (Rat) |
Description: | Q8R431 |
Residue: | 303 |
Sequence: | MPEASSPRRTPQNVPYQDLPHLVNADGQYLFCRYWKPSGTPKALIFVSHGAGEHCGRYDE
LAQMLKRLDMLVFAHDHVGHGQSEGERMVVSDFQVFVRDLLQHVNTVQKDYPEVPVFLLG
HSMGGAISILAAAERPTHFSGMILISPLILANPESASTLKVLAAKLLNFVLPNISLGRID
SSVLSRNKSEVDLYNSDPLICHAGVKVCFGIQLLNAVSRVERAMPRLTLPFLLLQGSADR
LCDSKGAYLLMESSPSQDKTLKMYEGAYHVLHKELPEVTNSVLHEINTWVSHRIAVAGAR
CLP
|
|
|
BDBM50274152 |
---|
n/a |
---|
Name | BDBM50274152 |
Synonyms: | (2S,9Z)-octadec-9-ene-1,2-diamine dihydrochloride | CHEMBL500707 |
Type | Small organic molecule |
Emp. Form. | C18H38N2 |
Mol. Mass. | 282.5077 |
SMILES | CCCCCCCC\C=C/CCCCCC[C@H](N)CN |r| |
Structure |
|