| Reaction Details |
|---|
 | Report a problem with these data |
| Target | B-cell receptor CD22 |
|---|
| Ligand | BDBM50274281 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_537287 (CHEMBL985383) |
|---|
| IC50 | 132320±n/a nM |
|---|
| Citation |  Abdu-Allah, HH; Tamanaka, T; Yu, J; Zhuoyuan, L; Sadagopan, M; Adachi, T; Tsubata, T; Kelm, S; Ishida, H; Kiso, M Design, synthesis, and structure-affinity relationships of novel series of sialosides as CD22-specific inhibitors. J Med Chem51:6665-81 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| B-cell receptor CD22 |
|---|
| Name: | B-cell receptor CD22 |
|---|
| Synonyms: | CD22 | CD22_HUMAN | SIGLEC2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 95348.60 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_727026 |
|---|
| Residue: | 847 |
|---|
| Sequence: | MHLLGPWLLLLVLEYLAFSDSSKWVFEHPETLYAWEGACVWIPCTYRALDGDLESFILFH
NPEYNKNTSKFDGTRLYESTKDGKVPSEQKRVQFLGDKNKNCTLSIHPVHLNDSGQLGLR
MESKTEKWMERIHLNVSERPFPPHIQLPPEIQESQEVTLTCLLNFSCYGYPIQLQWLLEG
VPMRQAAVTSTSLTIKSVFTRSELKFSPQWSHHGKIVTCQLQDADGKFLSNDTVQLNVKH
TPKLEIKVTPSDAIVREGDSVTMTCEVSSSNPEYTTVSWLKDGTSLKKQNTFTLNLREVT
KDQSGKYCCQVSNDVGPGRSEEVFLQVQYAPEPSTVQILHSPAVEGSQVEFLCMSLANPL
PTNYTWYHNGKEMQGRTEEKVHIPKILPWHAGTYSCVAENILGTGQRGPGAELDVQYPPK
KVTTVIQNPMPIREGDTVTLSCNYNSSNPSVTRYEWKPHGAWEEPSLGVLKIQNVGWDNT
TIACAACNSWCSWASPVALNVQYAPRDVRVRKIKPLSEIHSGNSVSLQCDFSSSHPKEVQ
FFWEKNGRLLGKESQLNFDSISPEDAGSYSCWVNNSIGQTASKAWTLEVLYAPRRLRVSM
SPGDQVMEGKSATLTCESDANPPVSHYTWFDWNNQSLPYHSQKLRLEPVKVQHSGAYWCQ
GTNSVGKGRSPLSTLTVYYSPETIGRRVAVGLGSCLAILILAICGLKLQRRWKRTQSQQG
LQENSSGQSFFVRNKKVRRAPLSEGPHSLGCYNPMMEDGISYTTLRFPEMNIPRTGDAES
SEMQRPPPDCDDTVTYSALHKRQVGDYENVIPDFPEDEGIHYSELIQFGVGERPQAQENV
DYVILKH
|
|
|
|---|
| BDBM50274281 |
|---|
| n/a |
|---|
| Name | BDBM50274281 |
|---|
| Synonyms: | CHEMBL502234 | p-Methoxyphenyl (3,5,9-trideoxy-5-glycolamido-9-nicotinoylamino-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2->6)-beta-D-galactopyranoside |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C30H39N3O16 |
|---|
| Mol. Mass. | 697.6412 |
|---|
| SMILES | COc1ccc(O[C@@H]2O[C@H](CO[C@@]3(C[C@H](O)[C@@H](NC(=O)CO)[C@@H](O3)[C@H](O)[C@H](O)CNC(=O)c3cccnc3)C(O)=O)[C@H](O)[C@H](O)[C@H]2O)cc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
