| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 1 |
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| Ligand | BDBM50273944 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_537978 (CHEMBL1032434) |
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| Ki | 43±n/a nM |
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| Citation |  Weiss, S; Keller, M; Bernhardt, G; Buschauer, A; König, B Modular synthesis of non-peptidic bivalent NPY Y1 receptor antagonists. Bioorg Med Chem16:9858-66 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide Y receptor type 1 |
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| Name: | Neuropeptide Y receptor type 1 |
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| Synonyms: | NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44399.07 |
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| Organism: | Homo sapiens (Human) |
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| Description: | NPY-Y1 NPY1R HUMAN::P25929 |
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| Residue: | 384 |
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| Sequence: | MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLA
LIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQ
CVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMT
DEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKR
RNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNL
LFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVS
KTSLKQASPVAFKKINNNDDNEKI
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| BDBM50273944 |
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| n/a |
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| Name | BDBM50273944 |
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| Synonyms: | (E)-{[4-(4-{4-[1-(4-{[(1Z)-Ammonio({(4R)-4-[(diphenylacetyl)amino]-5-[(4-hydroxybenzyl)amino]-5-oxopentyl}amino)methylene]amino}-4-oxobutyl)-1H-1,2,3-triazol-4-yl]phenyl}-1H-1,2,3-triazol-1-yl)butanoyl]amino}-({(4R)-4-[(diphenylacetyl)amino]-5-[(4-hydroxybenzyl)amino]-5-oxopentyl}imino)methanaminium bis(trifluoroacetate) | CHEMBL501317 |
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| Type | Small organic molecule |
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| Emp. Form. | C72H80N16O8 |
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| Mol. Mass. | 1297.5069 |
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| SMILES | [NH3+]C(NC(=O)CCCn1cc(nn1)-c1ccc(cc1)-c1cn(CCCC(=O)NC([NH3+])=NCCC[C@@H](NC(=O)C(c2ccccc2)c2ccccc2)C(=O)NCc2ccc(O)cc2)nn1)=NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1 |r,w:30.32,64.70| |
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| Structure | 
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