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TargetPurinergic receptor P2Y1
LigandBDBM50245983
Substrate/Competitorn/a
Meas. Tech.ChEMBL_558004
Ki 70±n/a nM
Citation Morales-Ramos AIMecom JSKiesow TJGraybill TLBrown GDAiyar NVDavenport EAKallal LAKnapp-Reed BALi PLondregan ATMorrow DMSenadhi SThalji RKZhao SBurns-Kurtis CLMarino JP Tetrahydro-4-quinolinamines identified as novel P2Y(1) receptor antagonists. Bioorg Med Chem Lett 18:6222-6 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Purinergic receptor P2Y1
Name:Purinergic receptor P2Y1
Synonyms:ATP receptor | P2Y purinoceptor 1 (P2Y1) | P2Y1 | Purinergic receptor
Type:Enzyme
Mol. Mass.:42090.25
Organism:Homo sapiens (Human)
Description:P47900
Residue:373
Sequence:
MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYIL
VFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFG
DAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVV
VAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLI
VRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFND
RVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLN
ILPEFKQNGDTSL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50245983
n/a
NameBDBM50245983
Synonyms:(2R,3S,4S)-2-Ethyl-3-methyl-N-[3,5-(chloro)phenyl]-4-(phenylamino)-3,4-dihydro-1(2H)-quinolinecarboxamide | (2R,3S,4S)-N-(3,5-dichlorophenyl)-2-ethyl-3-methyl-4-(phenylamino)-3,4-dihydroquinoline-1(2H)-carboxamide | CHEMBL462373
TypeSmall organic molecule
Emp. Form.C25H25Cl2N3O
Mol. Mass.454.392
SMILESCC[C@@H]1[C@@H](C)[C@H](Nc2ccccc2)c2ccccc2N1C(=O)Nc1cc(Cl)cc(Cl)c1 |r|
Structure
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