| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50273839 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_538318 (CHEMBL1036752) |
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| Ki | 182±n/a nM |
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| Citation |  Stefanachi, A; Nicolotti, O; Leonetti, F; Cellamare, S; Campagna, F; Loza, MI; Brea, JM; Mazza, F; Gavuzzo, E; Carotti, A 1,3-Dialkyl-8-(hetero)aryl-9-OH-9-deazaxanthines as potent A2B adenosine receptor antagonists: design, synthesis, structure-affinity and structure-selectivity relationships. Bioorg Med Chem16:9780-9 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36197.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P0DMS8 |
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| Residue: | 318 |
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| Sequence: | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
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| BDBM50273839 |
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| n/a |
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| Name | BDBM50273839 |
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| Synonyms: | 7-hydroxy-6-phenyl-1,3-dipropyl-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione | CHEMBL516154 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H21N3O3 |
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| Mol. Mass. | 327.3776 |
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| SMILES | CCCn1c2c(O)c([nH]c2c(=O)n(CCC)c1=O)-c1ccccc1 |
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| Structure | 
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