| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor delta |
|---|
| Ligand | BDBM50245782 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_558114 (CHEMBL959043) |
|---|
| EC50 | 7100±n/a nM |
|---|
| Citation |  Martres, P; Faucher, N; Laroze, A; Pineau, O; Fouchet, MH; Potvain, F; Grillot, D; Beneton, V The discovery of equipotent PPARalpha/gamma dual activators. Bioorg Med Chem Lett18:6251-4 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Peroxisome proliferator-activated receptor delta |
|---|
| Name: | Peroxisome proliferator-activated receptor delta |
|---|
| Synonyms: | NUC1 | Nr1c2 | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR-beta | PPAR-delta | PPARD_MOUSE | Pparb | Ppard |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 49719.14 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_1288931 |
|---|
| Residue: | 440 |
|---|
| Sequence: | MEQPQEETPEAREEEKEEVAMGDGAPELNGGPEHTLPSSSCADLSQNSSPSSLLDQLQMG
CDGASGGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCDRICKIQKKN
RNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTASEGCQHNPQLADLKAFSKH
IYNAYLKNFNMTKKKARSILTGKSSHNAPFVIHDIETLWQAEKGLVWKQLVNGLPPYNEI
SVHVFYRCQSTTVETVRELTEFAKNIPNFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKD
GLLVANGSGFVTHEFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDR
PGLMNVPQVEAIQDTILRALEFHLQVNHPDSQYLFPKLLQKMADLRQLVTEHAQMMQWLK
KTESETLLHPLLQEIYKDMY
|
|
|
|---|
| BDBM50245782 |
|---|
| n/a |
|---|
| Name | BDBM50245782 |
|---|
| Synonyms: | 2-(4-((5-(4-isopropylphenyl)-1-methyl-1H-pyrazole-3-carboxamido)methyl)-2-methylphenoxy)-2-methylpropanoic acid | CHEMBL455157 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H31N3O4 |
|---|
| Mol. Mass. | 449.542 |
|---|
| SMILES | CC(C)c1ccc(cc1)-c1cc(nn1C)C(=O)NCc1ccc(OC(C)(C)C(O)=O)c(C)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
