| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] A |
|---|
| Ligand | BDBM50273529 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_536001 (CHEMBL988017) |
|---|
| Ki | 6.5±n/a nM |
|---|
| Citation |  La Regina, G; Silvestri, R; Gatti, V; Lavecchia, A; Novellino, E; Befani, O; Turini, P; Agostinelli, E Synthesis, structure-activity relationships and molecular modeling studies of new indole inhibitors of monoamine oxidases A and B. Bioorg Med Chem16:9729-40 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Amine oxidase [flavin-containing] A |
|---|
| Name: | Amine oxidase [flavin-containing] A |
|---|
| Synonyms: | AOFA_BOVIN | Amine oxidase [flavin-containing] A | MAO-A | MAOA | Monoamine Oxidase Type A (MAO-A) | Monoamine oxidase | Monoamine oxidase A | Monoamine oxidase type A |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 59764.63 |
|---|
| Organism: | Bos taurus |
|---|
| Description: | ChEMBL_1501477 |
|---|
| Residue: | 527 |
|---|
| Sequence: | MESLQKTSDAGQMFDVVVIGGGISGLSAAKLLAEHEVNVLVLEARERVGGRTYTVRNEHV
DYVDVGGAYVGPTQNRILRLSKQLGLETYKVNVNERLVHYVKGKTYPFRGAFPPVWNPIA
YLDYNNLWRTMDNMGKEIPADAPWEAPHAVEWDKMTMKDLIEKICWTKTARQFASLFVNI
NVTSEPHEVSALWFLWYVKQCGGTTRIFSITNGGQERKFVGGSGQVSERIMQLLGDRVKL
RSPVTYVDQSSENITVETLNRELYECRYVISAIPPTLTAKIHFRPELPSERNQLIQRLPM
GAVIKCMMYYKEAFWKKKDYCGCMIIEDEEAPISITLDDTKPDGSLPAIMGFILARKADR
LAKVHKDIRKRKICELYAKVLGSQEALHPVHYEEKNWCQEQYSGGCYTAYFPPGIMTQYG
RVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALGKLSAKDIWIQEPEAED
VPAVEITPSFWERNLPSVSGLLKIVGFSTSITALWFVMYRFRLLSRS
|
|
|
|---|
| BDBM50273529 |
|---|
| n/a |
|---|
| Name | BDBM50273529 |
|---|
| Synonyms: | CHEMBL503807 | N-Methyl,N-(2-phenylethyl)-1-methyl-1H-indole-2-carboxamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H20N2O |
|---|
| Mol. Mass. | 292.3749 |
|---|
| SMILES | CN(CCc1ccccc1)C(=O)c1cc2ccccc2n1C |
|---|
| Structure | 
|
|---|
Search and Browse
