| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Envelope glycoprotein gp70 |
|---|
| Ligand | BDBM50273850 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_536775 (CHEMBL984569) |
|---|
| IC50 | 9400±n/a nM |
|---|
| Citation |  LaFrate, AL; Gunther, JR; Carlson, KE; Katzenellenbogen, JA Synthesis and biological evaluation of guanylhydrazone coactivator binding inhibitors for the estrogen receptor. Bioorg Med Chem16:10075-84 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Envelope glycoprotein gp70 |
|---|
| Name: | Envelope glycoprotein gp70 |
|---|
| Synonyms: | ENV_MMTVG | env |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 77236.72 |
|---|
| Organism: | Mouse mammary tumor virus (strain GR) (MMTV) |
|---|
| Description: | ChEMBL_536775 |
|---|
| Residue: | 688 |
|---|
| Sequence: | MPNHQSGSPTGSSDLLLSGKKQRPHLALRRKRRREMRKINRKVRRMNLAPIKEKTAWQHL
QALISEAEEVLKTSQTPQNSLTLFLALLSVLGPPPVTGESYWAYLPKPPILHPVGWGSTD
PIRVLTNQTMYLGGSPDFHGFRNMSGNVHFEGKSDTLPICFSFSFSTPTGCFQVDKQVFL
SDTPTVDNNKPGGKGDKRRMWELWLHTLGNSGANTKLVPIKKKLPPKYPHCQIAFKKDAF
WEGDESAPPRWLPCAFPDKGVSFSPKGALGLLWDFSLPSPSVDQSDQIKSKKDLFGNYTP
PVNKEVHRWYEAGWVEPTWFWENSPKDPNDRDFTALVPHTELFRLVAASRHLILKRPGFQ
EHEMIPTSACVTYPYAILLGLPQLIDIEKRGSTFHISCSSCRLTNCLDSSAYDYAAIIVK
RPPYVLLPVDIGDEPWFDDSAIQTFRYATDLIRAKRFVAAIILGISALIAIITSFAVATT
ALVKEMQTATFVNNLHRNVTLALSEQRIIDLKLEARLNALEEVVLELGQDVANLKTRMST
RCHANYDFICVTPLPYNATEDWERTRAHLLGIWNDNEISYNIQELTNLISDMSKQHIDAV
DLSGLAQSFANGVKALNPLDWTQYFIFIGVGALLLVIVLMIFPIVFQCLAKSLDQVQSDL
NVLLLKKKKGGNAAPAAEMVELPRVSYT
|
|
|
|---|
| BDBM50273850 |
|---|
| n/a |
|---|
| Name | BDBM50273850 |
|---|
| Synonyms: | 1-Chloro-3-dihydro-4-methylnaphthalene-2-carboxaldehyde guanylhydrazone | CHEMBL456393 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H15ClN4 |
|---|
| Mol. Mass. | 262.738 |
|---|
| SMILES | [#6]-[#6]-1-[#6]-[#6](-[#6]=[#7]\[#7]=[#6](\[#7])-[#7])=[#6](Cl)-c2ccccc-12 |w:4.3,t:9| |
|---|
| Structure | 
|
|---|
Search and Browse
