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TargetMotilin receptor
LigandBDBM50344942
Substrate/Competitorn/a
Meas. Tech.ChEMBL_559942
EC50 50.12±n/a nM
Citation Westaway SMBrown SLConway EHeightman TDJohnson CNLapsley KMacdonald GJMacPherson DTMitchell DJMyatt JWSeal JTStanway SJStemp GThompson MCelestini PColombo AConsonni AGagliardi SRiccaboni MRonzoni SBriggs MAMatthews KLStevens AJBolton VJBoyfield IJarvie EMStratton SCSanger GJ The discovery of biaryl carboxamides as novel small molecule agonists of the motilin receptor. Bioorg Med Chem Lett 18:6429-36 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Motilin receptor
Name:Motilin receptor
Synonyms:G-protein coupled receptor 38
Type:PROTEIN
Mol. Mass.:45365.95
Organism:Homo sapiens (Human)
Description:ChEMBL_122664
Residue:412
Sequence:
MGSPWNGSDGPEGAREPPWPALPPCDERRCSPFPLGALVPVTAVCLCLFVVGVSGNVVTV
MLIGRYRDMRTTTNLYLGSMAVSDLLILLGLPFDLYRLWRSRPWVFGPLLCRLSLYVGEG
CTYATLLHMTALSVERYLAICRPLRARVLVTRRRVRALIAVLWAVALLSAGPFLFLVGVE
QDPGISVVPGLNGTARIASSPLASSPPLWLSRAPPPSPPSGPETAEAAALFSRECRPSPA
QLGALRVMLWVTTAYFFLPFLCLSILYGLIGRELWSSRRPLRGPAASGRERGHRQTVRVL
LVVVLAFIICWLPFHVGRIIYINTEDSRMMYFSQYFNIVALQLFYLSASINPILYNLISK
KYRAAAFKLLLARKSRPRGFHRSRDTAGEVAGDTGGDTVGYTETSANVKTMG
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  Blast E-value cutoff:
BDBM50344942
n/a
NameBDBM50344942
Synonyms:CHEMBL532 | E-MYCIN E | ERYTHROMYCIN | ERYTHROMYCIN ETHYLSUCCINATE | Erycette | Erymax | Erythromycin A | Erythromycin C | Ilotycin | T-Stat
TypeSmall organic molecule
Emp. Form.C37H67NO13
Mol. Mass.733.9268
SMILESCC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O |r|
Structure
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