| Reaction Details |
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 | Report a problem with these data |
| Target | Peptide deformylase |
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| Ligand | BDBM50255003 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_559976 (CHEMBL1014575) |
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| IC50 | 8±n/a nM |
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| Citation |  Pichota, A; Duraiswamy, J; Yin, Z; Keller, TH; Alam, J; Liung, S; Lee, G; Ding, M; Wang, G; Chan, WL; Schreiber, M; Ma, I; Beer, D; Ngew, X; Mukherjee, K; Nanjundappa, M; Teo, JW; Thayalan, P; Yap, A; Dick, T; Meng, W; Xu, M; Koehn, J; Pan, SH; Clark, K; Xie, X; Shoen, C; Cynamon, M Peptide deformylase inhibitors of Mycobacterium tuberculosis: synthesis, structural investigations, and biological results. Bioorg Med Chem Lett18:6568-72 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptide deformylase |
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| Name: | Peptide deformylase |
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| Synonyms: | DEF_MYCTU | def |
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| Type: | PROTEIN |
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| Mol. Mass.: | 20931.95 |
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| Organism: | Mycobacterium tuberculosis |
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| Description: | ChEMBL_559976 |
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| Residue: | 197 |
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| Sequence: | MAVVPIRIVGDPVLHTATTPVTVAADGSLPADLAQLIATMYDTMDAANGVGLAANQIGCS
LRLFVYDCAADRAMTARRRGVVINPVLETSEIPETMPDPDTDDEGCLSVPGESFPTGRAK
WARVTGLDADGSPVSIEGTGLFARMLQHETGHLDGFLYLDRLIGRYARNAKRAVKSHGWG
VPGLSWLPGEDPDPFGH
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| BDBM50255003 |
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| n/a |
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| Name | BDBM50255003 |
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| Synonyms: | CHEMBL519613 | N-((R)-3-((S)-2-(1H-benzo[d]imidazol-2-yl)pyrrolidin-1-yl)-2-(cyclopropylmethyl)-3-oxopropyl)-N-hydroxyformamide |
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| Type | Small organic molecule |
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| Emp. Form. | C19H24N4O3 |
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| Mol. Mass. | 356.4189 |
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| SMILES | ON(C[C@@H](CC1CC1)C(=O)N1CCC[C@H]1c1nc2ccccc2[nH]1)C=O |r| |
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| Structure | 
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