Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetPeptide deformylase
LigandBDBM50255065
Substrate/Competitorn/a
Meas. Tech.ChEMBL_559976 (CHEMBL1014575)
IC50 18±n/a nM
Citation Pichota, ADuraiswamy, JYin, ZKeller, THAlam, JLiung, SLee, GDing, MWang, GChan, WLSchreiber, MMa, IBeer, DNgew, XMukherjee, KNanjundappa, MTeo, JWThayalan, PYap, ADick, TMeng, WXu, MKoehn, JPan, SHClark, KXie, XShoen, CCynamon, M Peptide deformylase inhibitors of Mycobacterium tuberculosis: synthesis, structural investigations, and biological results. Bioorg Med Chem Lett18:6568-72 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Peptide deformylase
Name:Peptide deformylase
Synonyms:DEF_MYCTU | def
Type:PROTEIN
Mol. Mass.:20931.95
Organism:Mycobacterium tuberculosis
Description:ChEMBL_559976
Residue:197
Sequence:
MAVVPIRIVGDPVLHTATTPVTVAADGSLPADLAQLIATMYDTMDAANGVGLAANQIGCS
LRLFVYDCAADRAMTARRRGVVINPVLETSEIPETMPDPDTDDEGCLSVPGESFPTGRAK
WARVTGLDADGSPVSIEGTGLFARMLQHETGHLDGFLYLDRLIGRYARNAKRAVKSHGWG
VPGLSWLPGEDPDPFGH
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50255065
n/a
NameBDBM50255065
Synonyms:(S)-2-((S)-2-(1H-benzo[d]imidazol-2-yl)pyrrolidine-1-carbonyl)-N-hydroxyhexanamide | CHEMBL464060
TypeSmall organic molecule
Emp. Form.C18H24N4O3
Mol. Mass.344.4082
SMILESCCCC[C@H](C(=O)NO)C(=O)N1CCC[C@H]1c1nc2ccccc2[nH]1 |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: