| Reaction Details |
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 | Report a problem with these data |
| Target | B1 bradykinin receptor |
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| Ligand | BDBM50254632 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_560708 (CHEMBL1010843) |
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| Ki | 1210±n/a nM |
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| Citation |  Cole, AG; Metzger, A; Brescia, MR; Qin, LY; Appell, KC; Brain, CT; Hallett, A; Ganju, P; Denholm, AA; Wareing, JR; Ritchie, TJ; Drake, GM; Bevan, SJ; MacGloinn, A; McBryde, A; Patel, V; Oakley, PJ; Nunez, X; Gstach, H; Schneider, P; Baldwin, JJ; Dolle, RE; McDonald, E; Henderson, I Sulfonamido-aryl ethers as bradykinin B1 receptor antagonists. Bioorg Med Chem Lett19:119-22 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| B1 bradykinin receptor |
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| Name: | B1 bradykinin receptor |
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| Synonyms: | B1 BRADYKININ | B1 bradykinin receptor | B1R | BDKRB1 | BK-1 receptor | BKRB1_HUMAN | BRADYB1 | Bradykinin B1 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 40508.87 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P46663 |
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| Residue: | 353 |
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| Sequence: | MASSWPPLELQSSNQSQLFPQNATACDNAPEAWDLLHRVLPTFIISICFFGLLGNLFVLL
VFLLPRRQLNVAEIYLANLAASDLVFVLGLPFWAENIWNQFNWPFGALLCRVINGVIKAN
LFISIFLVVAISQDRYRVLVHPMASRRQQRRRQARVTCVLIWVVGGLLSIPTFLLRSIQA
VPDLNITACILLLPHEAWHFARIVELNILGFLLPLAAIVFFNYHILASLRTREEVSRTRC
GGRKDSKTTALILTLVVAFLVCWAPYHFFAFLEFLFQVQAVRGCFWEDFIDLGLQLANFF
AFTNSSLNPVIYVFVGRLFRTKVWELYKQCTPKSLAPISSSHRKEIFQLFWRN
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| BDBM50254632 |
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| n/a |
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| Name | BDBM50254632 |
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| Synonyms: | 2-(2,4-dichloro-N-(2-(2,3-dihydro-1H-inden-5-yloxy)ethyl)phenylsulfonamido)-N-(3-methoxypropyl)acetamide | CHEMBL480203 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H28Cl2N2O5S |
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| Mol. Mass. | 515.45 |
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| SMILES | COCCCNC(=O)CN(CCOc1ccc2CCCc2c1)S(=O)(=O)c1ccc(Cl)cc1Cl |
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| Structure | 
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