| Reaction Details |
|---|
 | Report a problem with these data |
| Target | C-X-C chemokine receptor type 3 |
|---|
| Ligand | BDBM50254758 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_560734 (CHEMBL1010869) |
|---|
| IC50 | 158.49±n/a nM |
|---|
| Citation |  Wang, Y; Busch-Petersen, J; Wang, F; Kiesow, TJ; Graybill, TL; Jin, J; Yang, Z; Foley, JJ; Hunsberger, GE; Schmidt, DB; Sarau, HM; Capper-Spudich, EA; Wu, Z; Fisher, LS; McQueney, MS; Rivero, RA; Widdowson, KL Camphor sulfonamide derivatives as novel, potent and selective CXCR3 antagonists. Bioorg Med Chem Lett19:114-8 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| C-X-C chemokine receptor type 3 |
|---|
| Name: | C-X-C chemokine receptor type 3 |
|---|
| Synonyms: | CXCR3_MOUSE | Cmkar3 | Cxcr3 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 41020.84 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_560734 |
|---|
| Residue: | 367 |
|---|
| Sequence: | MYLEVSERQVLDASDFAFLLENSTSPYDYGENESDFSDSPPCPQDFSLNFDRTFLPALYS
LLFLLGLLGNGAVAAVLLSQRTALSSTDTFLLHLAVADVLLVLTLPLWAVDAAVQWVFGP
GLCKVAGALFNINFYAGAFLLACISFDRYLSIVHATQIYRRDPRVRVALTCIVVWGLCLL
FALPDFIYLSANYDQRLNATHCQYNFPQVGRTALRVLQLVAGFLLPLLVMAYCYAHILAV
LLVSRGQRRFRAMRLVVVVVAAFAVCWTPYHLVVLVDILMDVGVLARNCGRESHVDVAKS
VTSGMGYMHCCLNPLLYAFVGVKFREQMWMLFTRLGRSDQRGPQRQPSSSRRESSWSETT
EASYLGL
|
|
|
|---|
| BDBM50254758 |
|---|
| n/a |
|---|
| Name | BDBM50254758 |
|---|
| Synonyms: | (1S,2S,4R)-1-(((S)-4-(3-fluoro-5-(trifluoromethyl)pyridin-2-yl)-3-methylpiperazin-1-ylsulfonyl)methyl)-7,7-dimethylbicyclo[2.2.1]heptan-2-ol | CHEMBL464234 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H29F4N3O3S |
|---|
| Mol. Mass. | 479.532 |
|---|
| SMILES | C[C@H]1CN(CCN1c1ncc(cc1F)C(F)(F)F)S(=O)(=O)C[C@]12CC[C@H](C[C@@H]1O)C2(C)C |r,TLB:28:27:23.24:29| |
|---|
| Structure | 
|
|---|
Search and Browse
