| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 1 |
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| Ligand | BDBM50267086 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_565116 (CHEMBL965760) |
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| IC50 | 1100±n/a nM |
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| Citation |  Cao, S; Murphy, BT; Foster, C; Lazo, JS; Kingston, DG Bioactivities of simplified adociaquinone B and naphthoquinone derivatives against Cdc25B, MKP-1, and MKP-3 phosphatases. Bioorg Med Chem17:2276-81 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dual specificity protein phosphatase 1 |
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| Name: | Dual specificity protein phosphatase 1 |
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| Synonyms: | 3ch134 | DUS1_MOUSE | Dusp1 | Mkp1 | Ptpn10 | Ptpn16 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39372.46 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_565116 |
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| Residue: | 367 |
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| Sequence: | MVMEVGILDAGGLRALLREGAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAM
GLEHIVPNAELRGRLLAGAYHAVVLLDERSASLDGAKRDGTLALAAGALCREARSTQVFF
LQGGYEAFSASCPELCSKQSTPTGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILSF
LYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEA
IDFIDSIKDAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFS
FMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHPTNSALNYLKSP
ITTSPSC
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| BDBM50267086 |
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| n/a |
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| Name | BDBM50267086 |
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| Synonyms: | Adociaquinone B | CHEMBL476648 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H17NO6S |
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| Mol. Mass. | 423.438 |
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| SMILES | C[C@@]12CCCc3coc(c13)C(=O)c1cc3C(=O)C4=NCCS(=O)(=O)C4C(=O)c3cc21 |r,t:19| |
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| Structure | 
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