| Reaction Details |
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 | Report a problem with these data |
| Target | Atypical kinase COQ8B, mitochondrial |
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| Ligand | BDBM26145 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_537108 (CHEMBL988940) |
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| Kd | 129±n/a nM |
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| Citation |  Bamborough, P; Drewry, D; Harper, G; Smith, GK; Schneider, K Assessment of chemical coverage of kinome space and its implications for kinase drug discovery. J Med Chem51:7898-914 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Atypical kinase COQ8B, mitochondrial |
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| Name: | Atypical kinase COQ8B, mitochondrial |
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| Synonyms: | ADCK4 | COQ8B | COQ8B_HUMAN | Uncharacterized aarF domain-containing protein kinase 4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 60073.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_586944 |
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| Residue: | 544 |
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| Sequence: | MWLKVGGLLRGTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKFYQDGPGRGLGEEDIR
RAREARPRKTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAKKSMPGGRL
QSEGGSGLDSSPFLSEANAERIVQTLCTVRGAALKVGQMLSIQDNSFISPQLQHIFERVR
QSADFMPRWQMLRVLEEELGRDWQAKVASLEEVPFAAASIGQVHQGLLRDGTEVAVKIQY
PGIAQSIQSDVQNLLAVLKMSAALPAGLFAEQSLQALQQELAWECDYRREAACAQNFRQL
LANDPFFRVPAVVKELCTTRVLGMELAGGVPLDQCQGLSQDLRNQICFQLLTLCLRELFE
FRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHYIEVVKAAADGDRDCVLQKS
RDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGSGETARRIQDLIPVLLRHRLCP
PPEETYALHRKLAGAFLACAHLRAHIACRDLFQDTYHRYWASRQPDAATAGSLPTKGDSW
VDPS
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| BDBM26145 |
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| n/a |
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| Name | BDBM26145 |
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| Synonyms: | 2,4-dianilino pyrimidine, 2 | 3-({4-[(5-hydroxy-2-methylphenyl)amino]pyrimidin-2-yl}amino)benzamide | CHEMBL249097 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H17N5O2 |
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| Mol. Mass. | 335.3599 |
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| SMILES | Cc1ccc(O)cc1Nc1ccnc(Nc2cccc(c2)C(N)=O)n1 |
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| Structure | 
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