| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosine-protein kinase FRK |
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| Ligand | BDBM50273637 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_537126 (CHEMBL988960) |
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| Kd | 6±n/a nM |
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| Citation |  Bamborough, P; Drewry, D; Harper, G; Smith, GK; Schneider, K Assessment of chemical coverage of kinome space and its implications for kinase drug discovery. J Med Chem51:7898-914 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Tyrosine-protein kinase FRK |
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| Name: | Tyrosine-protein kinase FRK |
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| Synonyms: | FRK | FRK_HUMAN | FYN-related kinase | Nuclear tyrosine protein kinase RAK | PTK5 | RAK | SRC | Tyrosine Kinase FRK |
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| Type: | Tyrosine-protein kinase |
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| Mol. Mass.: | 58254.41 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P42685 |
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| Residue: | 505 |
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| Sequence: | MSNICQRLWEYLEPYLPCLSTEADKSTVIENPGALCSPQSQRHGHYFVALFDYQARTAED
LSFRAGDKLQVLDTLHEGWWFARHLEKRRDGSSQQLQGYIPSNYVAEDRSLQAEPWFFGA
IGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAVVKHYRIKRLDEGGFFLTRR
RIFSTLNEFVSHYTKTSDGLCVKLGKPCLKIQVPAPFDLSYKTVDQWEIDRNSIQLLKRL
GSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLREAQIMKNLRHPKLIQLYAVCTLED
PIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLESRNYIHRDLAARNV
LVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEAIRSNKFSIKSDVWSFG
ILLYEIITYGKMPYSGMTGAQVIQMLAQNYRLPQPSNCPQQFYNIMLECWNAEPKERPTF
ETLRWKLEDYFETDSSYSDANNFIR
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| BDBM50273637 |
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| n/a |
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| Name | BDBM50273637 |
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| Synonyms: | 3-(4-amino-7-(piperidin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenol | CHEMBL450519 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H19N5O |
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| Mol. Mass. | 309.3657 |
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| SMILES | Nc1ncnc2n(cc(-c3cccc(O)c3)c12)C1CCNCC1 |
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| Structure | 
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