| Reaction Details |
|---|
 | Report a problem with these data |
| Target | RAC-gamma serine/threonine-protein kinase |
|---|
| Ligand | BDBM50241256 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_538130 (CHEMBL1025773) |
|---|
| Kd | >10000±n/a nM |
|---|
| Citation |  Bamborough, P; Drewry, D; Harper, G; Smith, GK; Schneider, K Assessment of chemical coverage of kinome space and its implications for kinase drug discovery. J Med Chem51:7898-914 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| RAC-gamma serine/threonine-protein kinase |
|---|
| Name: | RAC-gamma serine/threonine-protein kinase |
|---|
| Synonyms: | AKT3 | AKT3_HUMAN | PKB gamma | PKBG | Protein kinase Akt-3 | Protein kinase B (Akt 3) | Protein kinase B, gamma | RAC-PK-gamma | RAC-gamma serine/threonine-protein kinase | STK-2 | Serine/threonine-protein kinase AKT | Serine/threonine-protein kinase AKT3 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 55769.36 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 479 |
|---|
| Sequence: | MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
PFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE
|
|
|
|---|
| BDBM50241256 |
|---|
| n/a |
|---|
| Name | BDBM50241256 |
|---|
| Synonyms: | CHEMBL233000 | N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)benzamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H14N2OS |
|---|
| Mol. Mass. | 282.36 |
|---|
| SMILES | O=C(Nc1sc2CCCCc2c1C#N)c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
