| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase STK11 |
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| Ligand | BDBM50273541 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_537062 (CHEMBL986211) |
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| Kd | 380±n/a nM |
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| Citation |  Bamborough, P; Drewry, D; Harper, G; Smith, GK; Schneider, K Assessment of chemical coverage of kinome space and its implications for kinase drug discovery. J Med Chem51:7898-914 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase STK11 |
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| Name: | Serine/threonine-protein kinase STK11 |
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| Synonyms: | LKB1 | PJS | STK11 | STK11_HUMAN | Serine/threonine-protein kinase 11 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 48640.33 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_655439 |
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| Residue: | 433 |
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| Sequence: | MEVVDPQQLGMFTEGELMSVGMDTFIHRIDSTEVIYQPRRKRAKLIGKYLMGDLLGEGSY
GKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNE
EKQKMYMVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPG
NLLLTTGGTLKISDLGVAEALHPFAADDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWS
AGVTLYNITTGLYPFEGDNIYKLFENIGKGSYAIPGDCGPPLSDLLKGMLEYEPAKRFSI
RQIRQHSWFRKKHPPAEAPVPIPPSPDTKDRWRSMTVVPYLEDLHGADEDEDLFDIEDDI
IYTQDFTVPGQVPEEEASHNGQRRGLPKAVCMNGTEAAQLSTKSRAEGRAPNPARKACSA
SSKIRRLSACKQQ
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| BDBM50273541 |
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| n/a |
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| Name | BDBM50273541 |
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| Synonyms: | CHEMBL516312 | N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)nicotinamide |
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| Type | Small organic molecule |
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| Emp. Form. | C20H13N5O |
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| Mol. Mass. | 339.3501 |
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| SMILES | O=C(Nc1c[nH]c2ncc(cc12)-c1ccc(cc1)C#N)c1cccnc1 |
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| Structure | 
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