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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | C-X-C chemokine receptor type 4 | ||
| Ligand | BDBM50035696 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_556954 (CHEMBL958140) | ||
| IC50 | 108±n/a nM | ||
| Citation |  Thoma, G; Streiff, MB; Kovarik, J; Glickman, F; Wagner, T; Beerli, C; Zerwes, HG Orally bioavailable isothioureas block function of the chemokine receptor CXCR4 in vitro and in vivo. J Med Chem51:7915-20 (2008) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| C-X-C chemokine receptor type 4 | |||
| Name: | C-X-C chemokine receptor type 4 | ||
| Synonyms: | C-X-C chemokine receptor type 4 | C-X-C chemokine receptor type 4 (CXCR4/SDF-1) | CXCR4_RAT | Cmkar4 | Cxcr4 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 39342.13 | ||
| Organism: | Rattus norvegicus (Rat) | ||
| Description: | O08565 | ||
| Residue: | 349 | ||
| Sequence: |
| ||
| BDBM50035696 | |||
| n/a | |||
| Name | BDBM50035696 | ||
| Synonyms: | 1,1''-{1,4-phenylenebis(methylene)}-bis{1,4,8,11-tetraaza-cyclotetradecane} | 1,4,8,11-tetraazacyclotetradecanyl[4-(1,4,8,11-tetraazacyclotetradecanylmethyl)phenyl]methane | 1,4,8,11-tetraazacyclotetradecanyl[4-(1,4,8,11-tetraazacyclotetradecanylmethyl)phenyl]methane(8HBr.2H2O) | 1,4-bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene | 11''-xylyl bis-1,4,8,11-tetraazacyclotetradecane | 11-{4-[4,8, 11-1,4,8,11tetraaza-cyclotetradec-1-ylmethyl]-benzyl}-1,4,8,11tetraaza-cyclotetradecane-1,4,8-tricarboxylic acid tri-tert-butyl ester | AMD-3100 | CHEMBL18442 | CHEMBL2311089 | PLERIXAFOR | PLERIXAFOR OCTAHYDROCHLORIDE | US9205085, MSX-162 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C28H54N8 | ||
| Mol. Mass. | 502.782 | ||
| SMILES | C(N1CCCNCCNCCCNCC1)c1ccc(CN2CCCNCCNCCCNCC2)cc1 | ||
| Structure | 
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