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TargetAmine oxidase [flavin-containing] B
LigandBDBM50246766
Substrate/Competitorn/a
Meas. Tech.ChEMBL_561011 (CHEMBL1015251)
Ki 28±n/a nM
Citation Milczek, EMBonivento, DBinda, CMattevi, AMcDonald, IAEdmondson, DE Structural and mechanistic studies of mofegiline inhibition of recombinant human monoamine oxidase B. J Med Chem51:8019-26 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Amine oxidase [flavin-containing] B
Name:Amine oxidase [flavin-containing] B
Synonyms:AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB)
Type:Protein
Mol. Mass.:58768.76
Organism:Homo sapiens (Human)
Description:P27338
Residue:520
Sequence:
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
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BDBM50246766
n/a
NameBDBM50246766
Synonyms:CHEMBL489079 | Mofegiline | US9302986, Mofegiline
TypeSmall organic molecule
Emp. Form.C11H13F2N
Mol. Mass.197.2244
SMILESNC\C(CCc1ccc(F)cc1)=C\F
Structure
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