| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Retinoic acid receptor beta |
|---|
| Ligand | BDBM50265951 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_544806 (CHEMBL1011986) |
|---|
| EC50 | 0.8±n/a nM |
|---|
| Citation |  Charton, J; Deprez-Poulain, R; Hennuyer, N; Tailleux, A; Staels, B; Deprez, B Novel non-carboxylic acid retinoids: 1,2,4-oxadiazol-5-one derivatives. Bioorg Med Chem Lett19:489-92 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Retinoic acid receptor beta |
|---|
| Name: | Retinoic acid receptor beta |
|---|
| Synonyms: | HAP | HBV-activated protein | NR1B2 | Nuclear receptor subfamily 1 group B member 2 | RAR-beta | RAR-epsilon | RARB | RARB_HUMAN | Retinoic acid receptor RXR-alpha/Retinoic acid receptor beta | Retinoic acid receptor beta | Retinoid receptor |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 50498.70 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1458015 |
|---|
| Residue: | 455 |
|---|
| Sequence: | MTTSGHACPVPAVNGHMTHYPATPYPLLFPPVIGGLSLPPLHGLHGHPPPSGCSTPSPAT
IETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNM
IYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKETSKQECTESYEM
TAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIV
EFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNA
GFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALK
IYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGH
EPLTPSSSGNTAEHSPSISPSSVENSGVSQSPLVQ
|
|
|
|---|
| BDBM50265951 |
|---|
| n/a |
|---|
| Name | BDBM50265951 |
|---|
| Synonyms: | CHEMBL1657 | TAZAROTENE | US9963439, Tazarotene | ethyl 6-[(4,4-dimethyl-3,4-dihydro-2H-thiochromen-6-yl)ethynyl]nicotinate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H21NO2S |
|---|
| Mol. Mass. | 351.462 |
|---|
| SMILES | CCOC(=O)c1ccc(nc1)C#Cc1ccc2SCCC(C)(C)c2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
