| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM50265981 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_540180 (CHEMBL1029809) |
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| Ki | 67±n/a nM |
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| Citation |  Cole, AG; Stauffer, TM; Rokosz, LL; Metzger, A; Dillard, LW; Zeng, W; Henderson, I Synthesis of 2-amino-5-benzoyl-4-(2-furyl)thiazoles as adenosine A(2A) receptor antagonists. Bioorg Med Chem Lett19:378-81 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44716.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P29274 |
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| Residue: | 412 |
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| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
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| BDBM50265981 |
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| n/a |
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| Name | BDBM50265981 |
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| Synonyms: | (4-(furan-2-yl)-2-(methylamino)thiazol-5-yl)(phenyl)methanone | CHEMBL461665 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H12N2O2S |
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| Mol. Mass. | 284.333 |
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| SMILES | CNc1nc(-c2ccco2)c(s1)C(=O)c1ccccc1 |
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| Structure | 
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