| Reaction Details |
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 | Report a problem with these data |
| Target | Arylamine N-acetyltransferase 1 |
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| Ligand | BDBM50275074 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_494096 (CHEMBL942268) |
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| IC50 | 138±n/a nM |
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| Citation |  Russell, AJ; Westwood, IM; Crawford, MH; Robinson, J; Kawamura, A; Redfield, C; Laurieri, N; Lowe, ED; Davies, SG; Sim, E Selective small molecule inhibitors of the potential breast cancer marker, human arylamine N-acetyltransferase 1, and its murine homologue, mouse arylamine N-acetyltransferase 2. Bioorg Med Chem17:905-18 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Arylamine N-acetyltransferase 1 |
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| Name: | Arylamine N-acetyltransferase 1 |
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| Synonyms: | AAC1 | ARY1_HUMAN | NAT1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 33898.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1347886 |
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| Residue: | 290 |
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| Sequence: | MDIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVV
RRNRGGWCLQVNHLLYWALTTIGFETTMLGGYVYSTPAKKYSTGMIHLLLQVTIDGRNYI
VDAGFGRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFLHSDL
LEDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVGFTLT
HRRFNYKDNTDLIEFKTLSEEEIEKVLKNIFNISLQRKLVPKHGDRFFTI
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| BDBM50275074 |
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| n/a |
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| Name | BDBM50275074 |
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| Synonyms: | (Z)-5-(3',5'-Diiodo-4'-hydroxybenzylidene)-2-thioxothiazolidine-4-one | CHEMBL458614 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H5I2NO2S2 |
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| Mol. Mass. | 489.091 |
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| SMILES | Oc1c(I)cc(C=C2SC(S)=NC2=O)cc1I |w:6.5,c:10| |
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| Structure | 
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