| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 5 |
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| Ligand | BDBM50277186 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_540421 (CHEMBL1029038) |
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| IC50 | 1.4±n/a nM |
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| Citation |  Evindar, G; Bernier, SG; Kavarana, MJ; Doyle, E; Lorusso, J; Kelley, MS; Halley, K; Hutchings, A; Wright, AD; Saha, AK; Hannig, G; Morgan, BA; Westlin, WF Synthesis and evaluation of alkoxy-phenylamides and alkoxy-phenylimidazoles as potent sphingosine-1-phosphate receptor subtype-1 agonists. Bioorg Med Chem Lett19:369-72 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sphingosine 1-phosphate receptor 5 |
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| Name: | Sphingosine 1-phosphate receptor 5 |
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| Synonyms: | EDG8 | Endothelial differentiation sphingolipid G-protein-coupled receptor 8 | S1P5 | S1PR5 | S1PR5_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-8 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 41796.42 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 398 |
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| Sequence: | MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLV
LGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALT
ASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLD
ACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRA
RRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSL
LNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSF
SGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD
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| BDBM50277186 |
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| n/a |
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| Name | BDBM50277186 |
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| Synonyms: | (R)-2-amino-2-(4-(4-(octyloxy)phenyl)-1H-imidazol-2-yl)propyl dihydrogen phosphate | CHEMBL474689 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H32N3O5P |
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| Mol. Mass. | 425.4589 |
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| SMILES | CCCCCCCCOc1ccc(cc1)-c1c[nH]c(n1)[C@@](C)(N)COP(O)(O)=O |r| |
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| Structure | 
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