| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50277226 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_540512 (CHEMBL1030616) |
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| Ki | 85±n/a nM |
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| Citation |  Goodman, AJ; Ajello, CW; Worm, K; Le Bourdonnec, B; Savolainen, MA; O'Hare, H; Cassel, JA; Stabley, GJ; Dehaven, RN; Labuda, CJ; Koblish, M; Little, PJ; Brogdon, BL; Smith, SA; Dolle, RE CB2 selective sulfamoyl benzamides: optimization of the amide functionality. Bioorg Med Chem Lett19:309-13 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 39690.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34972 |
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| Residue: | 360 |
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| Sequence: | MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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| BDBM50277226 |
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| n/a |
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| Name | BDBM50277226 |
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| Synonyms: | 4-(2-methyl-5-(5-neopentyl-1H-1,2,4-triazol-3-yl)phenylsulfonyl)morpholine | CHEMBL473697 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H26N4O3S |
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| Mol. Mass. | 378.489 |
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| SMILES | Cc1ccc(cc1S(=O)(=O)N1CCOCC1)-c1nnc(CC(C)(C)C)[nH]1 |
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| Structure | 
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