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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cycloartenol synthase | ||
| Ligand | BDBM50255600 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_515551 (CHEMBL1036572) | ||
| IC50 | 2000±n/a nM | ||
| Citation |  Balliano, G; Dehmlow, H; Oliaro-Bosso, S; Scaldaferri, M; Taramino, S; Viola, F; Caron, G; Aebi, J; Ackermann, J Oxidosqualene cyclase from Saccharomyces cerevisiae, Trypanosoma cruzi, Pneumocystis carinii and Arabidopsis thaliana expressed in yeast: a model for the development of novel antiparasitic agents. Bioorg Med Chem Lett19:718-23 (2009) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cycloartenol synthase | |||
| Name: | Cycloartenol synthase | ||
| Synonyms: | CAS1 | CAS1_ARATH | CYC | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 86025.20 | ||
| Organism: | Arabidopsis thaliana | ||
| Description: | ChEMBL_956102 | ||
| Residue: | 759 | ||
| Sequence: |
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| BDBM50255600 | |||
| n/a | |||
| Name | BDBM50255600 | ||
| Synonyms: | CHEMBL481208 | N,N-diethyl-5-(4-(N-methyl-4-(trifluoromethyl)phenylsulfonamido)cyclohexyl)pentanamide | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H35F3N2O3S | ||
| Mol. Mass. | 476.596 | ||
| SMILES | CCN(CC)C(=O)CCCC[C@H]1CC[C@@H](CC1)N(C)S(=O)(=O)c1ccc(cc1)C(F)(F)F |r,wU:14.17,wD:11.10,(2.4,-7.24,;1.07,-8,;1.07,-9.54,;-.26,-10.31,;-1.6,-9.54,;2.4,-10.31,;2.4,-11.84,;3.73,-9.54,;5.06,-10.31,;6.39,-9.54,;7.72,-10.31,;9.06,-9.54,;10.39,-10.31,;11.73,-9.54,;11.72,-7.99,;10.39,-7.23,;9.06,-8,;13.04,-7.23,;13.04,-5.69,;14.37,-7.99,;15.71,-8.77,;13.61,-9.33,;15.14,-6.66,;14.42,-5.3,;15.24,-3.98,;16.78,-4.04,;17.5,-5.4,;16.68,-6.71,;17.6,-2.74,;18.41,-1.45,;18.9,-3.56,;16.3,-1.93,)| | ||
| Structure | 
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