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TargetTranslocator protein
LigandBDBM50255877
Substrate/Competitorn/a
Meas. Tech.ChEMBL_515651 (CHEMBL1029743)
Ki 0.997000±n/a nM
Citation Briard, EZoghbi, SSSiméon, FGImaizumi, MGourley, JPShetty, HULu, SFujita, MInnis, RBPike, VW Single-step high-yield radiosynthesis and evaluation of a sensitive 18F-labeled ligand for imaging brain peripheral benzodiazepine receptors with PET. J Med Chem52:688-99 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Translocator protein
Name:Translocator protein
Synonyms:BZRP | MBR | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor-related protein | Peripheral-type benzodiazepine receptor | TSPO | TSPO_HUMAN
Type:Enzyme
Mol. Mass.:18834.74
Organism:Homo sapiens (Human)
Description:P30536
Residue:169
Sequence:
MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAM
GYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAA
ATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE
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BDBM50255877
n/a
NameBDBM50255877
Synonyms:CHEMBL473435 | N-Fluoroacetyl-N-(2,5-dimethoxybenzyl)-2-phenoxyaniline
TypeSmall organic molecule
Emp. Form.C23H22FNO4
Mol. Mass.395.4235
SMILESCOc1ccc(OC)c(CN(C(=O)CF)c2ccccc2Oc2ccccc2)c1
Structure
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