| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-1 adrenergic receptor |
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| Ligand | BDBM50255804 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_516105 (CHEMBL983249) |
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| Ki | 47±n/a nM |
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| Citation |  Marona, H; Szkaradek, N; Rapacz, A; Filipek, B; Dybala, M; Siwek, A; Cegla, M; Szneler, E Preliminary evaluation of pharmacological properties of some xanthone derivatives. Bioorg Med Chem17:1345-52 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-1 adrenergic receptor |
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| Name: | Beta-1 adrenergic receptor |
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| Synonyms: | ADRB1R, B1AR | ADRB1_RAT | Adrb1 | Adrb1r | Adrenergic receptor beta | Beta-1 adrenoceptor | Beta-1 adrenoreceptor | adrenergic Beta1 | adrenergic Beta1,2 |
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| Type: | Protein |
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| Mol. Mass.: | 50486.84 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P18090 |
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| Residue: | 466 |
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| Sequence: | MGAGALALGASEPCNLSSAAPLPDGAATAARLLVLASPPASLLPPASEGSAPLSQQWTAG
MGLLLALIVLLIVVGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITLPFRYQSLLTRARARALVC
TVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLTGPPRPPSPAPSPSPGPPRPADSLANGRSSKRRP
SRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSA
FNPIIYCRSPDFRKAFQRLLCCARRAACRRRAAHGDRPRASGCLARAGPPPSPGAPSDDD
DDDAGATPPARLLEPWAGCNGGTTTVDSDSSLDEPGRQGFSSESKV
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| BDBM50255804 |
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| n/a |
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| Name | BDBM50255804 |
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| Synonyms: | 5-(3N-(2-Amino-2-methyl-1,3-dihydroxypropyl)-2-hydroxypropoxy)-3-chloro-9H-xanthen-9-one hydrochloride | CHEMBL481799 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H22ClNO6 |
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| Mol. Mass. | 407.845 |
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| SMILES | CC(CO)(CO)NCC(O)COc1cccc2c1oc1cc(Cl)ccc1c2=O |
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| Structure | 
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