| Reaction Details |
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 | Report a problem with these data |
| Target | Baculoviral IAP repeat-containing protein 3 |
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| Ligand | BDBM50255183 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_516266 (CHEMBL985936) |
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| Ki | 0.25±n/a nM |
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| Citation |  Sun, W; Nikolovska-Coleska, Z; Qin, D; Sun, H; Yang, CY; Bai, L; Qiu, S; Wang, Y; Ma, D; Wang, S Design, synthesis, and evaluation of potent, nonpeptidic mimetics of second mitochondria-derived activator of caspases. J Med Chem52:593-6 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Baculoviral IAP repeat-containing protein 3 |
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| Name: | Baculoviral IAP repeat-containing protein 3 |
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| Synonyms: | API2 | BIRC3 | BIRC3_HUMAN | Baculoviral IAP repeat-containing protein 3 | Baculoviral IAP repeat-containing protein 3 (IAP1 BIR3) | Inhibitor of apoptosis protein 3 (cIAP2) | MIHC | RNF49 | XIAP-BIR3 | cIAP1/cIAP2 |
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| Type: | Protein |
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| Mol. Mass.: | 68365.75 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13489 |
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| Residue: | 604 |
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| Sequence: | MNIVENSIFLSNLMKSANTFELKYDLSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGV
NDKVKCFCCGLMLDNWKRGDSPTEKHKKLYPSCRFVQSLNSVNNLEATSQPTFPSSVTNS
THSLLPGTENSGYFRGSYSNSPSNPVNSRANQDFSALMRSSYHCAMNNENARLLTFQTWP
LTFLSPTDLAKAGFYYIGPGDRVACFACGGKLSNWEPKDNAMSEHLRHFPKCPFIENQLQ
DTSRYTVSNLSMQTHAARFKTFFNWPSSVLVNPEQLASAGFYYVGNSDDVKCFCCDGGLR
CWESGDDPWVQHAKWFPRCEYLIRIKGQEFIRQVQASYPHLLEQLLSTSDSPGDENAESS
IIHFEPGEDHSEDAIMMNTPVINAAVEMGFSRSLVKQTVQRKILATGENYRLVNDLVLDL
LNAEDEIREEERERATEEKESNDLLLIRKNRMALFQHLTCVIPILDSLLTAGIINEQEHD
VIKQKTQTSLQARELIDTILVKGNIAATVFRNSLQEAEAVLYEHLFVQQDIKYIPTEDVS
DLPVEEQLRRLQEERTCKVCMDKEVSIVFIPCGHLVVCKDCAPSLRKCPICRSTIKGTVR
TFLS
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| BDBM50255183 |
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| n/a |
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| Name | BDBM50255183 |
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| Synonyms: | (1S,3S,6S,10aS)-1-benzyl-6-((S)-2-(methylamino)propanamido)-5-oxo-N-((R)-1,2,3,4-tetrahydronaphthalen-1-yl)decahydropyrrolo[1,2-a]azocine-3-carboxamide | CHEMBL475670 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H42N4O3 |
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| Mol. Mass. | 530.7009 |
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| SMILES | CN[C@@H](C)C(=O)N[C@H]1CCCC[C@H]2[C@@H](Cc3ccccc3)C[C@H](N2C1=O)C(=O)N[C@@H]1CCCc2ccccc12 |r| |
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| Structure | 
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