| Reaction Details |
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 | Report a problem with these data |
| Target | Low molecular weight phosphotyrosine protein phosphatase |
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| Ligand | BDBM50267069 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_563762 (CHEMBL993525) |
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| IC50 | 3100±n/a nM |
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| Citation |  Ottanà, R; Maccari, R; Ciurleo, R; Paoli, P; Jacomelli, M; Manao, G; Camici, G; Laggner, C; Langer, T 5-Arylidene-2-phenylimino-4-thiazolidinones as PTP1B and LMW-PTP inhibitors. Bioorg Med Chem17:1928-37 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Low molecular weight phosphotyrosine protein phosphatase |
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| Name: | Low molecular weight phosphotyrosine protein phosphatase |
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| Synonyms: | 3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c |
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| Type: | n/a |
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| Mol. Mass.: | 18042.81 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P24666 |
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| Residue: | 158 |
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| Sequence: | MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRG
QSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSY
DPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
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| BDBM50267069 |
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| n/a |
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| Name | BDBM50267069 |
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| Synonyms: | 4-{[4-Oxo-5-(4-phenoxybenzylidene)-2-phenyliminothiazolidin-3-yl]methyl}benzoic acid | CHEMBL478274 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H22N2O4S |
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| Mol. Mass. | 506.572 |
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| SMILES | OC(=O)c1ccc(CN2\C(S\C(=C/c3ccc(Oc4ccccc4)cc3)C2=O)=N\c2ccccc2)cc1 |
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| Structure | 
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