| Reaction Details |
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 | Report a problem with these data |
| Target | Potassium voltage-gated channel subfamily A member 3 |
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| Ligand | BDBM50279066 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_545452 (CHEMBL1032475) |
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| IC50 | 3600±n/a nM |
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| Citation |  Pegoraro, S; Lang, M; Dreker, T; Kraus, J; Hamm, S; Meere, C; Feurle, J; Tasler, S; Prütting, S; Kuras, Z; Visan, V; Grissmer, S Inhibitors of potassium channels KV1.3 and IK-1 as immunosuppressants. Bioorg Med Chem Lett19:2299-304 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Potassium voltage-gated channel subfamily A member 3 |
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| Name: | Potassium voltage-gated channel subfamily A member 3 |
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| Synonyms: | HGK5 | HLK3 | HPCN3 | HuKIII | KCNA3 | KCNA3_HUMAN | Potassium voltage-gated channel subfamily A member 3 | Voltage-gated potassium channel | Voltage-gated potassium channel subunit Kv1.3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 63835.47 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1513935 |
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| Residue: | 575 |
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| Sequence: | MDERLSLLRSPPPPSARHRAHPPQRPASSGGAHTLVNHGYAEPAAGRELPPDMTVVPGDH
LLEPEVADGGGAPPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLK
TLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIF
SEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVS
VLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVET
LCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSL
AILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE
ADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIV
SNFNYFYHRETEGEEQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHS
AFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV
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| BDBM50279066 |
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| n/a |
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| Name | BDBM50279066 |
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| Synonyms: | 5-(3-chlorophenylsulfonyl)-5H-dibenzo[b,d]azepin-7(6H)-one | CHEMBL496892 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H14ClNO3S |
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| Mol. Mass. | 383.848 |
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| SMILES | Clc1cccc(c1)S(=O)(=O)N1CC(=O)c2ccccc2-c2ccccc12 |
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| Structure | 
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