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TargetVoltage-gated potassium channel
LigandBDBM50279106
Substrate/Competitorn/a
Meas. Tech.ChEMBL_545452
IC50 10±n/a nM
Citation Pegoraro SLang MDreker TKraus JHamm SMeere CFeurle JTasler SPrütting SKuras ZVisan VGrissmer S Inhibitors of potassium channels KV1.3 and IK-1 as immunosuppressants. Bioorg Med Chem Lett 19:2299-304 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Voltage-gated potassium channel
Name:Voltage-gated potassium channel
Synonyms:HGK5 | HLK3 | HPCN3 | HuKIII | Potassium voltage-gated channel subfamily A member 3 | Voltage-gated potassium channel subunit Kv1.3
Type:PROTEIN
Mol. Mass.:63835.47
Organism:Homo sapiens (Human)
Description:ChEMBL_1513935
Residue:575
Sequence:
MDERLSLLRSPPPPSARHRAHPPQRPASSGGAHTLVNHGYAEPAAGRELPPDMTVVPGDH
LLEPEVADGGGAPPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLK
TLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIF
SEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVS
VLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVET
LCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSL
AILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE
ADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIV
SNFNYFYHRETEGEEQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHS
AFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV
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  Blast E-value cutoff:
BDBM50279106
n/a
NameBDBM50279106
Synonyms:4-(4-phenoxybutoxy)-7H-furo[3,2-g]chromen-7-one | 5-(4-phenoxybutoxy)psoralen | CHEMBL444449
TypeSmall organic molecule
Emp. Form.C21H18O5
Mol. Mass.350.3646
SMILESO=c1ccc2c(OCCCCOc3ccccc3)c3ccoc3cc2o1
Structure
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