Ki Summary

Reaction Details

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Target

Chitinase A

Ligand

BDBM50257243

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_562669 (CHEMBL1011828)

IC50

750±n/a nM

Citation

Sunazuka, T; Sugawara, A; Iguchi, K; Hirose, T; Nagai, K; Noguchi, Y; Saito, Y; Yamamoto, T; Ui, H; Gouda, H; Shiomi, K; Watanabe, T; Omura, S Argifin; efficient solid phase total synthesis and evaluation of analogues of acyclic peptide. Bioorg Med Chem17:2751-8 (2009) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

Chitinase A

Name:

Chitinase A

Synonyms:

CHIA_SERMA | chiA

Type:

PROTEIN

Mol. Mass.:

60981.21

Organism:

Serratia marcescens

Description:

ChEMBL_562669

Residue:

563

Sequence:

MRKFNKPLLALLIGSTLCSAAQAAAPGKPTIAWGNTKFAIVEVDQAATAYNNLVKVKNAA
DVSVSWNLWNGDAGTTAKILLNGKEAWSGPSTGSSGTANFKVNKGGRYQMQVALCNADGC
TASDATEIVVADTDGSHLAPLKEPLLEKNKPYKQNSGKVVGSYFVEWGVYGRNFTVDKIP
AQNLTHLLYGFIPICGGNGINDSLKEIEGSFQALQRSCQGREDFKVSIHDPFAALQKAQK
GVTAWDDPYKGNFGQLMALKQAHPDLKILPSIGGWTLSDPFFFMGDKVKRDRFVGSVKEF
LQTWKFFDGVDIDWEFPGGKGANPNLGSPQDGETYVLLMKELRAMLDQLSAETGRKYELT
SAISAGKDKIDKVAYNVAQNSMDHIFLMSYDFYGPFDLKNLGHQTALNAPAWKPDTAYTT
VNGVNALLAQGVKPGKVVVGTAMYGRGWTGVNGYQNNIPFTGTATGPVKGTWKNGIVDYR
QIAGQFMSGEWQYTYDATAEAPYVFKPSTGDLITFDDARSVQAKGKYVLDKQLGGLFSWE
IDADNGDILNSMNASLGNSAGVQ

BDBM50257243

n/a

Name

BDBM50257243

Synonyms:

(2S)-2-[[(2S)-2-acetamido-5-[[N-(methylcarbamoyl)carbamimidoyl]amino]pentanoyl]-methyl-amino]-3-phenyl-propanoic acid | CHEMBL493316 | Dipeptide | N-Ac-Arg{N-omega-(N-methylcarbanoyl)}-N-methyl-Phe-OH | N-acetyl-Arg{N(omega)-(N-methylcarbamoyl)}-N-methyl-Phe

Type

Small organic molecule

Emp. Form.

C20H30N6O5

Mol. Mass.

434.4894

SMILES

CNC(=O)NC(N)=NCCC[C@H](NC(C)=O)C(=O)N(C)[C@@H](Cc1ccccc1)C(O)=O |r,w:7.7|

Structure