| Reaction Details |
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 | Report a problem with these data |
| Target | Thromboxane A2 receptor |
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| Ligand | BDBM50277939 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_501283 (CHEMBL971469) |
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| Ki | 42±n/a nM |
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| Citation |  Leblanc, Y; Roy, P; Dufresne, C; Lachance, N; Wang, Z; O'Neill, G; Greig, G; Denis, D; Mathieu, MC; Slipetz, D; Sawyer, N; Tsou, N Discovery of potent and selective DP1 receptor antagonists in the azaindole series. Bioorg Med Chem Lett19:2125-8 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Thromboxane A2 receptor |
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| Name: | Thromboxane A2 receptor |
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| Synonyms: | Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta |
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| Type: | Enyzme |
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| Mol. Mass.: | 37445.28 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21731 |
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| Residue: | 343 |
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| Sequence: | MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
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| BDBM50277939 |
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| n/a |
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| Name | BDBM50277939 |
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| Synonyms: | (+/-)-2-(4-(methylsulfonyl)-5-(naphthalen-1-ylthio)-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-6-yl)acetic acid | CHEMBL519862 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H22N2O4S2 |
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| Mol. Mass. | 466.572 |
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| SMILES | CS(=O)(=O)c1ccnc2n3CCCC(CC(O)=O)c3c(Sc3cccc4ccccc34)c12 |
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| Structure | 
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