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Target5-hydroxytryptamine receptor 1A (5-HT1A)
LigandBDBM50267740
Substrate/Competitorn/a
Meas. Tech.ChEMBL_563399
Ki 39±n/a nM
Citation Medina RASallander JBenhamú BPorras ECampillo MPardo LLópez-Rodríguez ML Synthesis of new serotonin 5-HT7 receptor ligands. Determinants of 5-HT7/5-HT1A receptor selectivity. J Med Chem 52:2384-92 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 1A (5-HT1A)
Name:5-hydroxytryptamine receptor 1A (5-HT1A)
Synonyms:5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A
Type:n/a
Mol. Mass.:46122.49
Organism:Homo sapiens (Human)
Description:n/a
Residue:422
Sequence:
MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT
RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN
SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RQ
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  Blast E-value cutoff:
BDBM50267740
n/a
NameBDBM50267740
Synonyms:1-{(2E)-4-[4-(1-Naphthyl)piperazin-1-yl]but-2-enyl}-1,3-dihydro-2H-indol-2-one | CHEMBL490645
TypeSmall organic molecule
Emp. Form.C26H27N3O
Mol. Mass.397.5121
SMILESO=C1Cc2ccccc2N1C\C=C\CN1CCN(CC1)c1cccc2ccccc12
Structure
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