Reaction Details |
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Target | 5-hydroxytryptamine receptor 5A |
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Ligand | BDBM50267510 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_563491 (CHEMBL961039) |
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Ki | >10000±n/a nM |
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Citation | Herth, MM; Kramer, V; Piel, M; Palner, M; Riss, PJ; Knudsen, GM; Rösch, F Synthesis and in vitro affinities of various MDL 100907 derivatives as potential 18F-radioligands for 5-HT2A receptor imaging with PET. Bioorg Med Chem17:2989-3002 (2009) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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5-hydroxytryptamine receptor 5A |
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Name: | 5-hydroxytryptamine receptor 5A |
Synonyms: | 5-HT-5 | 5-HT-5A | 5-hydroxytryptamine receptor 5 (5-HT5) | 5-hydroxytryptamine receptor 5A (5-HT5A) | 5HT5A_HUMAN | HTR5A | Serotonin (5-HT) receptor | Serotonin receptor 5A |
Type: | Enzyme |
Mol. Mass.: | 40266.25 |
Organism: | Homo sapiens (Human) |
Description: | P47898 |
Residue: | 357 |
Sequence: | MDLPVNLTSFSLSTPSPLETNHSLGKDDLRPSSPLLSVFGVLILTLLGFLVAATFAWNLL
VLATILRVRTFHRVPHNLVASMAVSDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIAC
DVLCCTASIWNVTAIALDRYWSITRHMEYTLRTRKCVSNVMIALTWALSAVISLAPLLFG
WGETYSEGSEECQVSREPSYAVFSTVGAFYLPLCVVLFVYWKIYKAAKFRVGSRKTNSVS
PISEAVEVKDSAKQPQMVFTVRHATVTFQPEGDTWREQKEQRAALMVGILIGVFVLCWIP
FFLTELISPLCSCDIPAIWKSIFLWLGYSNSFFNPLIYTAFNKNYNSAFKNFFSRQH
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BDBM50267510 |
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n/a |
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Name | BDBM50267510 |
Synonyms: | (3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-toluylphenylethyl)-piperidine-4-yl)-methanol | CHEMBL476839 |
Type | Small organic molecule |
Emp. Form. | C24H32FNO3 |
Mol. Mass. | 401.5142 |
SMILES | COc1c(OCCF)cccc1C(O)C1CCN(CCc2ccc(C)cc2)CC1 |
Structure |
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