| Reaction Details |
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 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
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| Ligand | BDBM50267554 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_563494 (CHEMBL961042) |
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| Ki | 1930±n/a nM |
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| Citation |  Herth, MM; Kramer, V; Piel, M; Palner, M; Riss, PJ; Knudsen, GM; Rösch, F Synthesis and in vitro affinities of various MDL 100907 derivatives as potential 18F-radioligands for 5-HT2A receptor imaging with PET. Bioorg Med Chem17:2989-3002 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(1A) dopamine receptor |
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| Name: | D(1A) dopamine receptor |
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| Synonyms: | DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A |
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| Type: | Enzyme |
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| Mol. Mass.: | 49303.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21728 |
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| Residue: | 446 |
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| Sequence: | MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTN
FFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVD
RYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLA
ETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKN
CQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGS
GETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIET
VSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPAL
SVILDYDTDVSLEKIQPITQNGQHPT
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| BDBM50267554 |
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| n/a |
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| Name | BDBM50267554 |
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| Synonyms: | 4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-toluylethyl)-piperidine | CHEMBL490632 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H30FNO3 |
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| Mol. Mass. | 399.4983 |
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| SMILES | COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(C)cc2)CC1 |
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| Structure | 
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