| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1D |
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| Ligand | BDBM50267509 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_563487 (CHEMBL961035) |
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| Ki | 3418±n/a nM |
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| Citation |  Herth, MM; Kramer, V; Piel, M; Palner, M; Riss, PJ; Knudsen, GM; Rösch, F Synthesis and in vitro affinities of various MDL 100907 derivatives as potential 18F-radioligands for 5-HT2A receptor imaging with PET. Bioorg Med Chem17:2989-3002 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1D |
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| Name: | 5-hydroxytryptamine receptor 1D |
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| Synonyms: | 5-HT-1D | 5-HT-1D-alpha | 5-HT1D | 5-hydroxytryptamine receptor 1D (5-HT1D) | 5HT1D_HUMAN | HTR1D | HTR1DA | HTRL | Serotonin (5-HT) receptor | Serotonin Receptor 1D |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 41920.63 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Receptor binding assays were performed using human clone stably expressed in CHO cells. |
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| Residue: | 377 |
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| Sequence: | MSPLNQSAEGLPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVL
TTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDIT
CCTASILHLCVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLFWRQAK
AQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRILNPPSLYGKRFT
TAHLITGSAGSSLCSLNSSLHEGHSHSAGSPLFFNHVKIKLADSALERKRISAARERKAT
KILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFN
EEFRQAFQKIVPFRKAS
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| BDBM50267509 |
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| n/a |
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| Name | BDBM50267509 |
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| Synonyms: | (3-(2-Fluorethoxy)-2-methoxyphenyl)-(1-(2-p-nitrophenylethyl)-piperidine-4-yl)-methanol | CHEMBL476838 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H29FN2O5 |
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| Mol. Mass. | 432.4852 |
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| SMILES | COc1c(OCCF)cccc1C(O)C1CCN(CCc2ccc(cc2)[N+]([O-])=O)CC1 |
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| Structure | 
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