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TargetAcetylcholine Binding protein
LigandBDBM50267883
Substrate/Competitorn/a
Meas. Tech.ChEMBL_563557
Ki 100±n/a nM
Citation Ulens CAkdemir AJongejan Avan Elk RBertrand SPerrakis ALeurs RSmit ABSixma TKBertrand Dde Esch IJ Use of acetylcholine binding protein in the search for novel alpha7 nicotinic receptor ligands. In silico docking, pharmacological screening, and X-ray analysis. J Med Chem 52:2372-83 (2009) [PubMed]  Article
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Acetylcholine Binding protein
Name:Acetylcholine Binding protein
Synonyms:ACh-binding protein | Acetylcholine-binding protein | Acetylcholine-binding protein (AchBP) | Acetylcholine-binding protein (Ls-AchBP) | AchBP
Type:n/a
Mol. Mass.:26055.52
Organism:Lymnaea stagnalis
Description:Soluble acetylcholine receptor
Residue:229
Sequence:
MRRNIFCLACLWIVQACLSLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEV
NEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQ
LARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDD
SEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRSEIL
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  Blast E-value cutoff:
BDBM50267883
n/a
NameBDBM50267883
Synonyms:8-Benzyl-3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yloxy)-8-aza-bicyclo[3.2.1]octane | CHEMBL491861
TypeSmall organic molecule
Emp. Form.C29H31NO
Mol. Mass.409.5625
SMILESC(N1C2CCC1CC(C2)OC1c2ccccc2CCc2ccccc12)c1ccccc1
Structure
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