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TargetMu-type opioid receptor
LigandBDBM50259286
Substrate/Competitorn/a
Meas. Tech.ChEMBL_500675 (CHEMBL966891)
Ki 126±n/a nM
Citation Ho, GDAnthes, JBercovici, ACaldwell, JPCheng, KCCui, XFawzi, AFernandez, XGreenlee, WJHey, JKorfmacher, WLu, SXMcLeod, RLNg, FTorhan, ASTan, ZTulshian, DVarty, GBXu, XZhang, H The discovery of tropane derivatives as nociceptin receptor ligands for the management of cough and anxiety. Bioorg Med Chem Lett19:2519-23 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Mu-type opioid receptor
Name:Mu-type opioid receptor
Synonyms:M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:44789.51
Organism:Homo sapiens (Human)
Description:P35372
Residue:400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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  Blast E-value cutoff:
BDBM50259286
n/a
NameBDBM50259286
Synonyms:8-(bis(2-chlorophenyl)methyl)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octane-3-carboxamide | CHEMBL466921
TypeSmall organic molecule
Emp. Form.C27H25Cl2FN2O
Mol. Mass.483.405
SMILESNC(=O)C1(CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl)c1ccc(F)cc1 |TLB:1:3:10:6.7|
Structure
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