| Reaction Details |
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 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] B |
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| Ligand | BDBM50259619 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_500941 (CHEMBL972369) |
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| Ki | 310±n/a nM |
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| Citation |  Van der Walt, EM; Milczek, EM; Malan, SF; Edmondson, DE; Castagnoli, N; Bergh, JJ; Petzer, JP Inhibition of monoamine oxidase by (E)-styrylisatin analogues. Bioorg Med Chem Lett19:2509-13 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Amine oxidase [flavin-containing] B |
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| Name: | Amine oxidase [flavin-containing] B |
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| Synonyms: | AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB) |
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| Type: | Protein |
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| Mol. Mass.: | 58768.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P27338 |
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| Residue: | 520 |
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| Sequence: | MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
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| BDBM50259619 |
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| n/a |
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| Name | BDBM50259619 |
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| Synonyms: | (E)-5-Styrylisatin | CHEMBL466872 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H11NO2 |
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| Mol. Mass. | 249.264 |
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| SMILES | O=C1Nc2ccc(\C=C\c3ccccc3)cc2C1=O |
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| Structure | 
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