| Reaction Details |
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 | Report a problem with these data |
| Target | Potassium voltage-gated channel subfamily A member 5 |
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| Ligand | BDBM50258801 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_499826 (CHEMBL972458) |
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| IC50 | 280±n/a nM |
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| Citation |  Gross, MF; Castle, NA; Zou, A; Wickenden, AD; Yu, W; Spear, KL Aryl sulfonamido tetralin inhibitors of the Kv1.5 ion channel. Bioorg Med Chem Lett19:3063-6 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Potassium voltage-gated channel subfamily A member 5 |
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| Name: | Potassium voltage-gated channel subfamily A member 5 |
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| Synonyms: | HK2 | HPCN1 | KCNA5 | KCNA5_HUMAN | Potassium voltage-gated channel subfamily A member 5 | Voltage-gated potassium channel | Voltage-gated potassium channel subunit Kv1.5 |
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| Type: | Enzyme |
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| Mol. Mass.: | 67222.47 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P22460 |
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| Residue: | 613 |
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| Sequence: | MEIALVPLENGGAMTVRGGDEARAGCGQATGGELQCPPTAGLSDGPKEPAPKGRGAQRDA
DSGVRPLPPLPDPGVRPLPPLPEELPRPRRPPPEDEEEEGDPGLGTVEDQALGTASLHHQ
RVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYYQ
SGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIKEEEKPLPRNEFQRQVWLIF
EYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGANG
SGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNII
DVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGL
QILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTMTT
VGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEEPAVLKEEQG
TQSQGPGLDRGVQRKVSGSRGSFCKAGGTLENADSARRGSCPLEKCNVKAKSNVDLRRSL
YALCLDTSRETDL
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| BDBM50258801 |
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| n/a |
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| Name | BDBM50258801 |
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| Synonyms: | (S)-N-(8-(4-ethylphenylsulfonamido)-5,6,7,8-tetrahydronaphthalen-2-yl)-3-phenylpropanamide | CHEMBL513656 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H30N2O3S |
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| Mol. Mass. | 462.604 |
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| SMILES | CCc1ccc(cc1)S(=O)(=O)N[C@H]1CCCc2ccc(NC(=O)CCc3ccccc3)cc12 |r| |
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| Structure | 
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