Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetPituitary adenylate cyclase-activating polypeptide type I receptor
LigandBDBM50250037
Substrate/Competitorn/a
Meas. Tech.ChEMBL_498611 (CHEMBL966957)
IC50 6.6±n/a nM
Citation Bourgault, SVaudry, DSégalas-Milazzo, IGuilhaudis, LCouvineau, ALaburthe, MVaudry, HFournier, A Molecular and conformational determinants of pituitary adenylate cyclase-activating polypeptide (PACAP) for activation of the PAC1 receptor. J Med Chem52:3308-16 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Pituitary adenylate cyclase-activating polypeptide type I receptor
Name:Pituitary adenylate cyclase-activating polypeptide type I receptor
Synonyms:ADCYAP1R1 | PACR_HUMAN
Type:PROTEIN
Mol. Mass.:53307.50
Organism:Homo sapiens (Human)
Description:ChEMBL_498617
Residue:468
Sequence:
MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDN
ITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTE
DGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRK
LHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSN
YFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMN
DSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYLRLARSTLLLIP
LFGIHYTVFAFSPENVSKRERLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWKV
NRYFAVDFKHRHPSLASSGVNGGTQLSILSKSSSQIRMSGLPADNLAT
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50250037
n/a
NameBDBM50250037
Synonyms:CHEMBL524894 | [D-Ser2]PACAP38
TypeSmall organic molecule
Emp. Form.C203H331N63O53S
Mol. Mass.4534.256
SMILESn/a
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: