| Reaction Details |
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 | Report a problem with these data |
| Target | Prolyl endopeptidase |
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| Ligand | BDBM50279827 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_157468 (CHEMBL765787) |
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| KON | 140000 M-1s-1 |
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| Citation |  Bakker, AV; Daffeh, J; Jung, S; Vincent, LA; Nagel, AA; Spencer, RW; Vinick, FJ; Faraci, WS Novel in vitro and in vivo inhibitors of prolyl endopeptidase Bioorg Med Chem Lett1:585-590 (1991) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prolyl endopeptidase |
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| Name: | Prolyl endopeptidase |
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| Synonyms: | PE | PPCE_MOUSE | Pep | Post-proline cleaving enzyme | Prep |
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| Type: | PROTEIN |
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| Mol. Mass.: | 80738.55 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1336164 |
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| Residue: | 710 |
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| Sequence: | MLSFQYPDVYRDETSVQEYHGHKICDPYSWLEDPDSEQTKAFVEAQNKITVPFLEQCPIR
GLYKERMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVFLDPNTLS
DDGTVALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFTCMAWTH
DGKGMFYNSYPQQDGKSDGTETSTNLHQKLCYHVLGTDQSEDILCAEFPDEPKWMGGAEL
SDDGRYVLLSIWEGCDPVNRLWYCDLQQEPNGITGILKWVKLIDNFEGEYDYVTNEGTVF
TFKTNRNSPNYRLINIDFTDPDESKWKVLVPEHEKDVLEWVACVRSNFLVLCYLHDVKNI
LQLHDLTTGALLKTFPLDVGSVVGYSGRKKDSEIFYQFTSFLSPGVIYHCDLTKEELEPM
VFREVTVKGIDAADYQTIQIFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNISI
TPNYSVSRLIFVRHMGGVLAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKE
GYTSPKRLTINGGSNGGLLVAACANQRPDLFGCVIAQVGVMDMLKFHKFTIGHAWTTDYG
CSDTKQHFEWLLKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSLKFIATLQYIV
GRSRKQSNPLLIHVDTKAGHGAGKPTAKVIEEVSDMFAFIARCLNIEWIQ
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| BDBM50279827 |
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| n/a |
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| Name | BDBM50279827 |
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| Synonyms: | 2-((S)-2-Formyl-pyrrolidine-1-carbonyl)-2,3-dihydro-indole-1-carboxylic acid benzyl ester | CHEMBL345903 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22N2O4 |
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| Mol. Mass. | 378.4211 |
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| SMILES | O=C[C@@H]1CCCN1C(=O)C1Cc2ccccc2N1C(=O)OCc1ccccc1 |
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| Structure | 
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