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Reaction Details
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TargetThromboxane A2 receptor
LigandBDBM50008805
Substrate/Competitorn/a
Meas. Tech.ChEBML_207649
Kd 2.9±n/a nM
Citation Ladouceur, GMais, DEJakubowski, JAUtterback, BGRobertson, DW Structural homologies among thromboxane (TXA2) receptor antagonists: Minimal pharmacophoric requirements for high affinity interaction with TXA2 receptors Bioorg Med Chem Lett1:173-178 (1991)    Article
More Info.:Get all data from this article,  Assay Method
 
Thromboxane A2 receptor
Name:Thromboxane A2 receptor
Synonyms:Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:Enyzme
Mol. Mass.:37445.28
Organism:Homo sapiens (Human)
Description:P21731
Residue:343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50008805
n/a
NameBDBM50008805
Synonyms:7-(3-Benzenesulfonylamino-bicyclo[2.2.1]hept-2-yl)-hept-5-enoic acid | CHEMBL56941 | S 145 | S-145,(+)
TypeSmall organic molecule
Emp. Form.C20H27NO4S
Mol. Mass.377.498
SMILESOC(=O)CCC\C=C/C[C@H]1[C@@H]2CCC(C2)C1NS(=O)(=O)c1ccccc1
Structure
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