| Reaction Details |
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 | Report a problem with these data |
| Target | Tubulin alpha-1A chain |
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| Ligand | BDBM50280008 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_212054 |
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| Ki | 2500±n/a nM |
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| Citation |  Hahn, KM; Humphreys, W; Helms, AM; Hastie, SB; Macdonald, TL Structural requirements for the binding of colchicine analogs to tubulin: the role of the C-10 substituent Bioorg Med Chem Lett1:471-476 (1991) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Tubulin alpha-1A chain |
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| Name: | Tubulin alpha-1A chain |
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| Synonyms: | TBA1A_PIG | TUBA1A | Tubulin | Tubulin alpha chain | Tubulin alpha-1A chain |
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| Type: | Protein |
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| Mol. Mass.: | 50049.25 |
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| Organism: | Sus scrofa (Pig) |
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| Description: | P02550 |
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| Residue: | 451 |
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| Sequence: | MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD
RIRKLADQCTGLQGFSVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA
VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA
SLRFDGALNVDLTEFQTNLVPYPRAHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN
QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYEPP
TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE
AREDMAALEKDYEEVGVDSVEGEGEEEGEEY
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| BDBM50280008 |
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| n/a |
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| Name | BDBM50280008 |
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| Synonyms: | 2-Methylamino-5-(2,3,4-trimethoxy-phenyl)-cyclohepta-2,4,6-trienone | CHEMBL145740 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H19NO4 |
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| Mol. Mass. | 301.3371 |
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| SMILES | CNc1ccc(ccc1=O)-c1ccc(OC)c(OC)c1OC |
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| Structure | 
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