| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histamine H3 receptor |
|---|
| Ligand | BDBM22911 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_85832 |
|---|
| IC50 | 4.6±n/a nM |
|---|
| Citation |  Howson, W; Parsons, ME; Raval, P; Swayne, GT Two novel, potent and selective histamine H3 receptor agonists Bioorg Med Chem Lett2:77-78 (1992) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Histamine H3 receptor |
|---|
| Name: | Histamine H3 receptor |
|---|
| Synonyms: | HISTAMINE H3 | HRH3 | HRH3_CAVPO | Histamine H3 receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 48753.61 |
|---|
| Organism: | GUINEA PIG |
|---|
| Description: | HISTAMINE H3 HRH3 GUINEA PIG::Q9JI35 |
|---|
| Residue: | 445 |
|---|
| Sequence: | MERAPPDGLMNASGALAGEAAAAAGGARTFSAAWTAVLAALMALLIVATVLGNALVMLAF
VADSSLRTQNNFFLLNLAISDFLVGVFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCT
SSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMVLVWVLAFLLYGPAILSWEYLSG
GSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGARE
AGPDPLPEAQSSPPQPPPGCWGCWPKGQGESMPLHRYGVGEAGPGAEAGEAALGGGSGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHSSLEHCWK
|
|
|
|---|
| BDBM22911 |
|---|
| n/a |
|---|
| Name | BDBM22911 |
|---|
| Synonyms: | 2-(3H-imidazol-4-yl)ethylsulfanylmethanimidamide | CHEMBL19439 | CHEMBL544911 | Imetit | {[2-(1H-imidazol-4-yl)ethyl]sulfanyl}methanimidamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C6H10N4S |
|---|
| Mol. Mass. | 170.235 |
|---|
| SMILES | NC(=N)SCCc1cnc[nH]1 |
|---|
| Structure | 
|
|---|
Search and Browse
