| Reaction Details |
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 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor |
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| Ligand | BDBM50009714 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_36160 |
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| IC50 | 420±n/a nM |
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| Citation |  Murray, WV; Lalan, P; Gill, A; Addo, MF; Lewis, JM; Lee, DK; Rampulla, R; Wachter, MP; Hsi, JD; Underwood, DC Substituted piperidin-2-one biphenyltetrazoles as angiotensin II antagonists Bioorg Med Chem Lett2:1775-1779 (1992) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-1 angiotensin II receptor |
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| Name: | Type-1 angiotensin II receptor |
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| Synonyms: | AGTR1 | AGTR1_BOVIN | Angiotensin II type 1a (AT-1a) receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41107.81 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_36779 |
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| Residue: | 359 |
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| Sequence: | MILNSSTEDGIKRIQDDCPKAGRHNYIFIMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPTIIHRNVFFIENTNITVC
AFHYESQNSTLPVGLGLTKNILGFLFPFLIILTSYTLIWKTLKKAYEIQKNKPRKDDIFK
IILAIVLFFFFSWVPHQIFTFMDVLIQLGLIRDCKIEDIVDTAMPITICLAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSENGNSSTKKPAPCIEVE
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| BDBM50009714 |
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| n/a |
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| Name | BDBM50009714 |
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| Synonyms: | CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-3H-imidazol-4-yl}-methanol(DuP 753) |
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| Type | Small organic molecule |
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| Emp. Form. | C22H25ClN6O |
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| Mol. Mass. | 424.927 |
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| SMILES | CCCCC1=NC(Cl)C(CO)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 |t:4| |
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| Structure | 
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