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TargetAngiotensin II type 1a (AT-1a) receptor
LigandBDBM50280325
Substrate/Competitorn/a
Meas. Tech.ChEBML_36160
IC50 90±n/a nM
Citation Murray WVLalan PGill AAddo MFLewis JMLee DKRampulla RWachter MPHsi JDUnderwood DC Substituted piperidin-2-one biphenyltetrazoles as angiotensin II antagonists Bioorg Med Chem Lett 2:1775-1779 (1992)    Article
More Info.:Get all data from this article,  Assay Method
 
Angiotensin II type 1a (AT-1a) receptor
Name:Angiotensin II type 1a (AT-1a) receptor
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:41107.81
Organism:Bos taurus
Description:ChEMBL_36779
Residue:359
Sequence:
MILNSSTEDGIKRIQDDCPKAGRHNYIFIMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPTIIHRNVFFIENTNITVC
AFHYESQNSTLPVGLGLTKNILGFLFPFLIILTSYTLIWKTLKKAYEIQKNKPRKDDIFK
IILAIVLFFFFSWVPHQIFTFMDVLIQLGLIRDCKIEDIVDTAMPITICLAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSENGNSSTKKPAPCIEVE
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  Blast E-value cutoff:
BDBM50280325
n/a
NameBDBM50280325
Synonyms:CHEMBL48459 | [4-Ethyl-6-oxo-4-propyl-1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-piperidin-(2E)-ylidene]-acetic acid ethyl ester
TypeSmall organic molecule
Emp. Form.C28H33N5O3
Mol. Mass.487.5933
SMILESCCCC1(CC)CC(=O)N(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)\C(C1)=C\C(=O)OCC
Structure
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